So players are not allowed to build multiple small businesses on one large lot.
The Sims can possibly own a multiple business at once but there can only be one retail store per lot. The site wrote that in the 'Sims 4 Get to Work' a business must only have up to three employees at one time and this does not include the Sims from the player's active household. The developer has recently unveiled the 'Sims 4 Get to Work' official retail gameplay trailer and the TS4New share a detailed information about the retail career.